They are only 20 miles apart yet have barely played each other.
Indeed, the last time MK Dons hosted Luton Town was in November 2004 at the former National Hockey Stadium.
Contrasting promotions and relegations means their paths have not crossed until Saturday’s League One game at Stadium MK (12:30 BST)
They are not rivals as such, nor is the fixture comparable with Luton’s traditional, deep-seated hatred of Watford.
That is altogether different.
Still, for some Hatters fans, the resentment towards MK Dons runs deep.
Many remain angry about the controversial move of Wimbledon to Milton Keynes in 2003, a so-called ‘franchise team’ encroaching in their own backyard.
They saw it as a betrayal of a club and its community.
“I don’t dislike Milton Keynes, I dislike what they stand for,” said Mike Fanning, a Luton Town fan.
“They’re a franchise and that’s not what football is about.
“It’s a working men’s game, about a club and its community and it matters. It can’t be taken away. You can’t up sticks and go elsewhere because someone wants you to.”
